Viagra Science: viagra chemical and structure
Viagra: chemical and structure
Sildenafil citrate of drug viagra, grant calls and, help in general treatment man erectile dysfunction (impotence). Drug was developed by the Pfizer drug company.
Erection was developed first viagra treats heart disease (angina) increase the effect that attempt in research became the light. Drug acquires patent in 1996 after two years at the three month 27, 1998 (the becoming authorization by the treatment of Pilkington type of the first, FDA erectile failure), FDA provide authorization for sale, of it since 1998.
viagra and typing market was viagra, success soon succeed in the market. Is viagra prescription by patient use as much as possible, even TV, radio, Internet directly advertising was. According to the $ 1 billion to one estimate, annual sales viagra 1999 and 2001 Super got.
mechanism of the viagra: erectile physiology to in the release of nitric oxide (NO), corpus cavernosum to good feature viagra work. This leads to level the enhanced recharges enzyme guanylate, cyclic ganoshin monophosphate (cGMP). inflow of blood to the point engorgement, erection and writing extensions to corpus cavernosum smooth muscle of.
Degradation of the corpus cavernosum cGMP, Sildenafil cGMP specific phosphodiesterase 5 (PDE5), serves as the prominent is a strong selective inhibitor. In other words, lead to better viagra and sexual stimulation of the normal erections, of the corpus cavernosum cGMP enhanced level of. No, because recharging of the NO/cGMP system, viagra does not occur to the erection, sexual stimulation is required.
Viagra is by the liver enzyme metabolism and are exhausted by the liver and kidney. The valid plasma concentration viagra located some delay if high fat diet can be reduced for low of the absorbed. Cause viagra of blood flow to pleasure vagina of women of to some may increase some reports.