Treatment of erektil’noy disfunction.
Contra-indications: Hypersensitiveness; a simultaneous reception of organic nitrates is in any forms (see is “Pharmacology”, Influence on HELL at a simultaneous reception with nitrates); concomitant treatment al’fa-adrenoblokatorami (except for a 0,4 mg of tamsulozina 1 time per days) (see is “Co-operation”).
Limitations to application: Tadalafil is not shown for application for women, children (tadalafil did not estimate for patients younger 18 years), new-born.
Diseases of the serdechno-sosudistoy system:
- heart attack of miokarda during preceding 90 days;
- unstable stenokardiya or stenokardiya, arising up during sexual intercourse;
- cardiac insufficiency (class II and higher on classification of NYHA), developing during the last 6 mes;
Diagnosed inherited degenerative diseases of retina, including pigmental retinit.
Predisposition to priapizmu (falcate-cellular anaemia, plural mieloma, leukemia), anatomic deformation of cock (angular curvature, kavernoznyy fibroz, illness of Peyroni).
Heavy hepatic insufficiency.
Application at pregnancy and suckling:
Actions of sides: For period of conducting of clinical tests in the whole world tadalafil adopted over 5700 men in age 19–87 years (middle ages 59 years), over 1000 patients — during 1 and more, over 1300 patients — 6 mes and more. In platsebo-kontroliruemykh clinical tests of Phase 3 stake of patients, gettings 10 or 20 mgs of tadalafila and cuttings treatment short from the origin of effects of sides, 3,1% made by comparison to 1,4% for platsebo.
The effects of sides, which was observed for patients, are presented in a table, gettings tadalafil in the recommended doses (10 or 20 mgs), during conducting 8 basic platsebo-kontroliruemykh of clinical tests of Phase 3, including research at patients by saccharine diabetes (unfavorable effects, marked no less what for 2% patients and exceedings on frequency of met such in the group of platsebo, are indicated).